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Fostering Pragmatic Comparative-Effectiveness Trials in Non-communicable Diseases (EffecTrial)

The Research Council of Norway is announcing NOK 10 million to Norwegian researchers who want to participate in transnational investigator-initiated clinical studies.

The aims of the call are to to to support randomized, interventional and pragmatic comparative-effectiveness multi-country Investigator-Initiated Clinical Studies (IICS) and to encourage and enable transnational collaboration between clinical/public health research  teams (from hospital/ public health, healthcare settings and other healthcare organisations) that  conduct comparative-effectiveness multi-country IICS. 

Proposals should address all the 4 following points: 

  1. Be a pragmatic comparative effectiveness trials, designed as randomised interventional trials. 
  2. Compare the use of currently approved healthcare interventions either to each other or to the current standard of care. 
  3. They shall consider healthcare interventions which could include but would not be limited to: diagnostic, screening, prevention and treatment interventions. The interventions can be pharmacological as well as non-pharmacological procedures like nutrition and/or lifestyle 
    interventions, surgery, prognosis methods, use of medical devices, eHealth and digital interventions and other health interventions. 
  4. These interventions shall have high public relevance only in the fields of these specific diseases or conditions (that are of equal importance): Cardiovascular diseases, Metabolic disorders, Nutrition and lifestyle-related diseases and Non-communicable respiratory diseases

Website: https://era4health.eu/calls/effectrial2025.php

Messages at time of print 8 September 2026, 08:47 CEST

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