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7) Antioxidant-rich berries and oxidative stress

Sammendrag: It is well documentet that fruits and vegetables reduce risk of several diseases such as cancer, cardiovaslular disease, and cataract.

In order to test the hypothesis that this benefiecial effect is due to antioxidants we have systematically assessed antioxidants in a variety of dietary plants used worldwide including various fruits, berries, vegetables, cereals, nuts and pulses. Total concentration of antioxidants is assessed as the combined concentration of all electron-donating reductants.

Our results demonstrates that there is more than a thousand fold difference between total antioxidants in various dietary plants. Plants that contain most antioxidants include members of several families, such as Rocaceae (Dog rose, sour cherry, blackberry, strawberry, raspberry), Empetraceae (crowberry), Ericacea (blueberry), Grossulariaceae (blackcurrant), Lacythidaceae (Brazil nut), Juglandaceae (walnut), Asteraceae (sunflower seed), Punicaceae (pomegranate) and Zingiberaceae (ginger).

Thus, berries are the plant category containg most antioxidants. In the present project we will test the effect of antioxidant-rich berries on oxidative stress related gene expression. Furthermore, we aim at studying absorption of berry antioxidants and screening new variants og berries for their antioxidant capacities.

Prosjektnummer: 154342

Kontraktspartner: Institutt for ernæringsforskning, Universitetet i Oslo

Samarbeidspartnere: Radiumhospitalet, NLH, Universitetet i Oslo, Sverige, Tyskland, Belgia, Nederland, Spania, USA, Japan Prosjektleder: Professor Rune Blomhoff Post. doc. på prosjektet: Mari Myhrstad Status: Pågående (Prosj.nr.7) Prosjektperiode: 01.01.03 – 31.12.05 Forskningsrådsbevilgning: 2003 kr 1 000 000,- 2004 kr 1 000 000,- 2005 kr 1 000 000,-

Skrevet av:
Eva Elisabeth Haugen Seniorkonsulent 22 03 75 40 eeh@forskningsradet.no
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